Our Group
Dr. Darrell Mousseau's major research objective is to determine which biochemical events are common to depression and Alzheimer disease (AD) so as to identify modifable targets in the depressed brain that could stay the onset of AD in vulnerable individuals. His research also examines depression-related targets in models of diabetes (insulin resistance) and in breast cancer. The Cell Signalling Laboratory collaborates with individuals across the U of S campus and Canada.
Current Projects
- Activity-based probe development for MAOs
- Role of insulin signalling in MAO function
- Presenilin-1 splice viariants in aging
- Cannabinoid receptors and enzymes in the Alzheimer brain
- Antidepressants and the risk of dementia
- Using patient-derived brain organoids to study Alzheimer disease and Amyotrophic lateral sclerosis
Dr. Darrell Mousseau, PI
Darrell D. Mousseau is a Professor with the Department of Psychiatry. He received his Ph.D. (in Neurochemistry) from the University of Alberta, and did postdoctoral training at the University of Minnesota and at the Université de Montréal. He joined the University of Saskatchewan in 2002 where he established the Cell Signalling Laboratory. He is the Saskatchewan Research Chair in Alzheimer’s disease and related dementia funded jointly by the Alzheimer Society of Saskatchewan and the Saskatchewan Health Research Foundation.
Our Team
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From L-R: Dr. Tyler Wenzel (Post-doctoral Researcher), Justin Lukan (Lab Technician), Ryan Heistad (Lab Manager), and Dr. Darrell Mousseau (PI). |
