Dr. Darrell Mousseau's major research objective is to determine which biochemical events are common to depression and Alzheimer disease (AD) so as to identify modifable targets in the depressed brain that could stay the onset of AD in vulnerable individuals. His research also examines depression-related targets in models of diabetes (insulin resistance) and in breast cancer. The Cell Signalling Laboratory collaborates with individuals across the U of S campus and Canada.

•  Activity-based probe development for MAOs
•  Role of insulin signalling in MAO function
•  Presenilin-1 splice viariants in aging
•  Cannabinoid receptors and enzymes in the Alzehimer brain
•  Antidepressants and the risk of dementia

Darrell D. Mousseau is a Professor with the Department of Psychiatry. He received his Ph.D. (in Neurochemistry) from the University of Alberta, and did postdoctoral training at the University of Minnesota and at the Université de Montréal. He joined the University of Saskatchewan in 2002 where he established the Cell Signalling Laboratory. He is the Saskatchewan Research Chair in Alzheimer’s disease and related dementia funded jointly by the Alzheimer Society of Saskatchewan and the Saskatchewan Health Research Foundation.

Laboratory Manager Paul R. Pennington	Research Associate Dr. Jennifer Nyarko	Lab Technicians Ryan M. Heistad Justin Lukan
MSc students George-Paul O'Byrne Cameron Morse Jim He	PhD students Carla Almendariz Palacios