2022-23
BMIS 405 Structure and Function of Biomolecules (Membrane Transport)
This is a lecture-based course that focuses on the advanced principles of protein structure, stability and biological function. In addition, techniques used to study protein structure are introduced and illustrated with practical examples and problems. The membrane transport chapter covers structure and physical properties of lipid bilayer, thermodynamics of membrane protein folding, fundamental principles of ion transport across the membrane, and the mechanism of various membrane transporters, including bacteriorhodopsin, transport ATPases, secondary active transporters and ion channels.
BMIS 489 Extended Research Approaches in Biochemistry
The student will work two full terms on an undergraduate honors research project. In the process, the student will become familiar with the pertinent research literature, perform experiments according to the plan developed together with the supervisor, write a progress report, and a final report in the form of research paper, and give a talk on his or her findings to the department faculty and students. In our lab, the projects are usually based on protein NMR techniques.
Previous years
BMSC 200 Biomolecules
An introduction to the structures, general properties, and functions of simple and complex biomolecules: amino acids, peptides, proteins, enzymes, carbohydrates, lipids and nucleic acids as well as membranes and solute transport.
BIOC 898 Advanced Topics in Membrane Transport
This is a seminar for graduate students interested in the most recent advances in the area of membrane transport, structure and mechanism of membrane transport proteins. The instructor leads the discussion of selected recent publications. At the end of the course, the students write a review on the mechanism of a membrane transporter of their choice.
BMST 408/808 Methods of Protein Structure Determination (Protein NMR)
This was a combined senior undergraduate and graduate course covering principles of protein structure, and protein structure determination by X-ray crystallography and protein NMR.
BMST 406 Advanced Biomolecular Techniques
Combined lecture and lab course on biophysical methods covering circular dichroism (CD) and fluorescence spectroscopy, isothermal titration calorimetry (ITC), surface plasmon resonance (SPR), molecular modeling, and protein NMR.