Current Publications

[1]. A. Rajaram, D. J. Schreyer and X. B. Chen, 2015, “Use of the Polycation Polyethyleneimine to Improve the Physical Properties of Alginate-Hyaluronic Acid Hydrogel During Fabrication of Tissue Repair Scaffolds,” Journal of Biomaterials Science: Polymer Edition, 26(7), 433-445.

[2]. Md. S. Hossain, X. B. Chen, and D. J. Bergstrom, 2015 “Fluid Flow and Mass Transfer over Circular Cylinder(s) Using Lattice Boltzmann Method,” Heat and Mass Transfer, published online 15 February 2015 (DOI 10.1007/s00231-015-1514-6).  

[3]. M. Izadifar, M. Kelly, A. Haddadi, and X. B. Chen, 2015, “Optimization of Nanoparticles for Cardiovascular Tissue Engineering,” Nanotechnology, 26(23), 235301.

[4]. P. Zhai, X. B. Chen, and D. J. Schreyer, 2015 “PLGA/Alginate Composite Microspheres for Hydrophilic Protein Delivery,” Materials Science and Engineering C, 56, 251-259.

[5]. R. Fang, S. P. Qiao, Y. Liu, Q.Y. Meng, X. B. Chen, B. Song, X. L. Hou, and W. M. Tian, 2015, “Sustained Co-Delivery of BIO and IGF-1 by a Novel Hybrid Hydrogel System to Stimulate Endogenous Cardiac Repair in Myocardial Infarcted Rat Hearts,” International Journal of Nanomedicine , 10, 4691.

[6]. Md. Sarker, X. B. Chen, and D. J. Schreyer, 2015, “Experimental Approaches to Vascularization within Tissue Engineering Constructs,” Journal of Biomaterials Science: Polymer Edition, 26(12), 683-734

[7]. P. Zhai, X. B. Chen, and D. J. Schreyer, 2015 “An in vitro Study of Peptide-Loaded Alginate Nanospheres for Antagonizing the Inhibitory Effect of Nogo-A Protein on Axonal Growth,” Biomedical Materials 10(4): 045016.  

[8]. Z. Izadifar, A. Honaramooz, S. Wiebe, G. Belev, X. B. Chen and D. Chapman, 2015 “Low-Dose Phase-based X-ray Imaging Techniques for In Situ Soft Tissue Engineering Assessments,” Biomaterials (in press). (IF: 8.557).

[9]. X. B. Chen, 2014, “Dispensed-Based Bio-Manufacturing Scaffolds for Tissue Engineering Applications,” International Journal on Engineering Applications, 2(1).

[10]. A. Olubamiji, Z. Izadifar, and X. B. Chen, 2014, “Synchrotron imaging techniques for bone and cartilage tissue engineering: potentials, current trends, and future directions,” Tissue Engineering Part, 20(5): 503-22 (IF: 4.022).

[11]. X. Y. Tian and X. B. Chen, 2014, “Effects of Cell Density on Mechanical Properties of Alginate Hydrogel Tissue Scaffolds,” Journal of Biomimetics, Biomaterials, and Tissue Engineering, 19: 77-85.

[12]. S. Z. Liu, J. Y. Peng, Y. B. Zhang, and X. B. Chen, 2014, “Modeling Rotary-Screw-Driven Dispensing Systems for Electronics Packaging,” IEEE Trans. on Components, Packaging and Manufacturing Technology, 4(8): 1359-1365 (IF: 1.261).

[13]. M. Izadifar, M. Kelly, and X. B. Chen, 2014, “Engineering Angiogenesis for Myocardial Infarction Repair: Recent Developments, Challenges, and Future Directions,” Cardiovascular Engineering and Technology, 5(4): 281-307.

[14]. C. Little, W. Kulyk, and X. B. Chen, 2014, “Effect of Chondroitin Sulphate and Hyaluronic Acid on Chondrocytes,” Journal of Functional Biomaterials 5(3): 197-210.

[15]. A. Rajaram, D. J. Schreyer, and X. B. Chen, 2014, “Bioplotting Alginate-Hyaluronic Acid Hydrogel Scaffolds with Structural Integrity and Preserved Schwann Cell Viability," 3D Printing and Additive Manufacturing 1(4): 194-203.

[16]. S. Hossain, D. J. Bergstrom, and X. B. Chen, 2014 “Prediction of Cell Growth Rate over Scaffold Strands Inside a Perfusion Bioreactor,” Biomechanics and Modeling in Mechanobiology, 14(2), 333-344.

[17]. M. Izadifar, A. Haddadi, X. B. Chen and M. Kelly, 2014, “Rate-Programming of Nano-Particulate Delivery Systems for Smart Bioactive Scaffolds in Tissue Engineering,” Nanotechnology, 26(1), 012001.

[18]. M. G. Li, X. Y. Tian J. A. Kozinski, X. B. Chen, and D. K. Hwang, 2014, “Modeling Mechanical Cell Damage in Bioprinting Process Employing a Conical Needle”, Journal of Mechanics in Medicine and Biology, 1550073.

[19]. Z. Izadifar, L.D. Chapman, and X. B. Chen, 2013, “Computer Tomography Diffraction Enhanced Imaging for in situ Visualization of Tissue Scaffolds Implanted in Cartilage," Tissue Engineering Part C, 20(2): 140-8  (IF: 4.022).

[20]. M. D. Wang, P. Zhai, D. J. Schreyer, R. S. Zheng, X. D. Sun, F. Z. Cui, and X. B. Chen, 2013, “Novel Crosslinked Alginate/Hyaluronic Acid Hydrogels for Nerve Tissue Engineering,” Frontiers of Materials Science, 7(3): 269-284.

[21]. S. L. Yao, X. Liu, X. M. Wang, A. Merollic, X. B. Chen, F. Z. Cui, 2013, “Directing Neural Stem Cell Fate with Biomaterial Parameters for Injured Brain Regeneration,” Progress in Natural Science: Materials International, 23(2):103–112 (IF: 1.035).

[22]. X. Y. Tian, M. G. Li, and X. B. Chen, 2013, “Bio-Rapid-Prototyping of Tissue Engineering Scaffolds and the Process-Induced Call Damage,” Journal of Biomimetics, Biomaterials, and Tissue Engineering, vol.17, pp 1-23.

[23]. X. P. Bai, R. Fang, S. Zhang, S. L. Shi, Z. L. Wang, X. B. Chen, J. Y. Yang, X. L. Hou, Y. Z. Nie, Y. Li, and W. M. Tian, 2013 “Self-Cross-Linkable Hydrogels Composed of Partially Oxidized Alginate and Gelatin for Myocardial Infarction Repair,” Journal of Bioactive and Compatible Polymers, 28(2): 123-140 (IF: 2.207).

[24]. P. Zhai, X. B. Chen, and D. J. Schreyer, 2013 “Preparation and Characterization of Alginate Microspheres for Sustained Protein Delivery within Tissue Scaffolds,” Biofabrication, 5(1):015009 (IF: 3.480).

[25]. H. J. Yan, Y. He, Y. B. Yin, X. M. Wang, F. Z. Cui, X. B. Chen, Y. Li, S. Zhang, Y. Z. Nie, and W. M. Tian, 2013, “Self-Assembled Monolayers with Different Chemical Group Substrates for the Study of MCF-7 Breast Cancer Cell Line Behavior,” Biomedical Materials, 8(3): 035008 (IF: 2.158).

[26]. A. Rajaram, X. B. Chen, D. J. Schreyer, 2012, “Strategic Design and Recent Fabrication Techniques for Bioengineered Tissue Scaffolds to Improve Peripheral Nerve Regeneration," Tissue Engineering Part B, 18(6): 454-467 (IF: 4.636).

[27]. S. Hossain, X. B. Chen, and D. J. Bergstrom, 2012 “Investigation into the in vitro Culture Process for Skeletal-Tissue-Engineered Constructs Using Computational Fluid Dynamics and Experimental Methods,” ASME Journal of Biomechanical Engineering, 134(12):121003 (IF: 1.9).

[28]. Z. Izadifar, X. B. Chen, and W. Kulyk, 2012 “Strategic Design and Fabrication of Engineered Scaffolds for Articular Cartilage Repair,” Journal of Functional Biomaterials, 3(4): 799-838.

[29]. N. Zhu, D. Cooper, H. Niu, and X. B. Chen, 2012, “A Study on the in vitro Degradation of Poly-L-Lactide/Chitosan-Microspheres Scaffolds,” Frontiers of Materials Science, 7(1): 76-82.

[30].  M. Izadifar and X. B. Chen, 2012, “Radio Frequency Heating of Implanted Tissue Engineered Scaffolds: Simulation and Experimental Studies,” Frontiers of Heat and Mass Transfer, 3: 043004.

[31]. H. Zheng, W. M. Tian, H. J. Yan, L. Yue, Y. Zhang, F. T. Han, X. B. Chen, and Y. Li, 2012, “Rotary Culture Promotes the Proliferation of MCF-7 Cells Encapsulated in Three-Dimensional Collagen-Alginate Hydrogels via Activation of ERK1/2-MAPK Pathway,” Biomedical Materials, 7(1):015003 (IF: 2.467).

[32]. N. Cao, X. B. Chen, and D. Schreyer, 2012, “Influence of Calcium Ions on Cell Survival and Proliferation in the Context of an Alginate Hydrogel," ISRN Chemical Engineering, 2012: 516461 (9pp).

[33]. H. X. Zheng, W. M. Tian, H. J. Yan, H. D. Jiang, S. S. Liu, L. Yu, F. Han, L. J.  Wei, X. B. Chen, Y. Li, 2012, “Expression of Estrogen Receptor α in Human Breast Cancer Cells Regulates Mitochondrial Oxidative Stress under Simulated Microgravity,” Advances in Space Research, 49(10):1432-1440 (IF: 1.076).

[34]. J. W. Li, E. Matias, N. Chen, C.-Y. Kim, J. Wang, J. Gorin, F. He, P. Thorpe, Y. Lu, W.F. Chen, P. Grochulski, X.B. Chen, and W.J. Zhang, 2011, “Investigations of Mechanical Vibrations for Beamlines at the Canadian Light Source,” Journal of Synchrotron Radiation, vol. 18, pp. 109-116 (IF: 2.335).

[35]. M. G. Li, X. Y. Tian, and X. B. Chen, 2011, “Temperature Effect on the Shear-Induced Cell Damage in Biofabrication," Artificial Organ, 35(7): 741-746 (IF: 1.719).

[36]. M. D. Wang, P. Zhai, X. B. Chen, D. J. Schreyer, X. D Sun, and F. Z. Cui, 2011, “Bioengineered Scaffolds for Spinal Cord Repair," Tissue Engineering Part B, vol. 17, no. 3, pp. 177-194 (IF: 4.636 and 5-year IF: 5.444).

[37]. C. J. Little, N. K. Bawolin, and X. B. Chen, 2011, “Mechanical Properties of Natural Cartilage and Tissue Engineered Constructs," Tissue Engineering Part B, 17(4): 213-227, 2011 (IF: 4.636 and 5-year IF: 5.444).

[38]. X. P. Bai, H. X. Zheng, R. Fang, T. R. Wang, X. L. Hou, Y. Li, X. B. Chen, W. M. Tian, 2011, “Fabrication of Engineered Heart Tissue Grafts from Alginate/Collagen Barium Composite Microbeads,” Biomedical Materials, 6(4): 045002 (10pp) (IF: 2.467).

[39]. N. Zhu, M. G. Li, D. Cooper, and X. B. Chen, 2011, “Development of Novel Hybrid Poly (L-lactide)/Chitosan Scaffolds Using Rapid Freeze Prototyping Technique,” Biofabrication,3(3): 034105 (9pp) (IF: 1.857).

[40]. N. Zhu, D. Chapman, D. Cooper, D. Schreyer, and X. B. Chen, 2011, “X-ray Diffraction Enhanced Imaging as a Novel Method to Visualize Low Density Scaffolds in Soft Tissue Engineering,” Tissue Engineering Part C, 17(11):1071-80 (IF: 4.636 and 5-year IF: 5.444).

[41]. M. G. Li, X. Y. Tian, D. J. Schreyer, and X. B. Chen, 2011, “Effect of Needle Geometry on Flow Rate and Cell Damage in the Dispensing-Based Biofabrication Process,” Biotechnology Progress, 27(6):1777-84 (IF: 2.178).

[42]. N. Zhu, X. B. Chen, and D. Chapman, 2010, “A Brief Review of Visualization Techniques for Nerve Tissue Engineering Applications,” Journal of Biomimetics, Biomaterials, and Tissue Engineering, vol. 7, pp. 81-99. 

[43]. M. G. Li, X. Y. Tian, N. Zhu, D. Schreyer, and X. B. Chen, 2010, “Modeling Process-Induced Cell Damage in the Bio-Dispensing Process," Tissue Engineering Part C, vol. 16, no. 3, pp. 533-542 (IF: 4.636 and 5-year IF: 5.444)

[44]. N. K. Bawolin, M. G. Li, X. B. Chen, and W. J. Zhang, 2010, “Modeling Material-Degradation-Induced Elastic Property of Tissue Engineering Scaffolds,” ASME Journal of Biomechanical Engineering, vol. 132, no. 11, pp. 111001-1-7 (IF: 1.6).

[45]. N. Zhu, M. G. Li, Y. J. Guan, D. J. Schreyer, and X. B. Chen, 2010, “Effect of Laminin Blended with Chitosan on Axon Guidance on Patterned Substrates,” Biofabrication, vol. 2, 045002 (IF: 1.857).

[46]. X. B. Chen, M. G. Li, and N. Cao, 2009, “Modeling of the Fluid Volume Transferred in Contact Dispensing Processes,” IEEE Trans. on Electronics Packaging Manufacturing, vol. 32, no. 3, pp. 133-137 (IF: 1.16).

[47]. M. G. Li, X. Y. Tian, and X. B. Chen, 2009, “Modeling of Flow Rate, Pore Size and Porosity for the Dispensing-Based Tissue Scaffolds Fabrication,” ASME Journal of Manufacturing Science and Engineering, vol. 131, pp. 034501-1-5.

[48]. X. Y. Tian, M.G. Li, N. Cao, J.W. Li, and X.B. Chen, 2009 "Characterization of Flow Behaviours of Alginate/Hydroxyapaptite Mixtures for Tissue Scaffold Fabrication" Biofabrication,  vol. 1, 045005 (IF: 1.857).

[49]. M. G. Li, X. Y. Tian, and X. B. Chen, 2009, “A Brief Review of Dispensing-Based Rapid Prototyping Techniques in Tissue Scaffold Fabrication,” Biofabrication, vol. 1, 032001 (IF: 1.857). N. K. Bawolin, W. J. Zhang, X. B. Chen, 2010, “A Brief Review of the Modelling of the Time Dependent Mechanical Properties of Tissue Engineering Scaffolds,” Journal of Biomimetics, Biomaterials, and Tissue Engineering, vol. 6, pp. 19-33.

[50].  X. B. Chen, M. G. Li, and H. Ke, 2008, “Modeling of the Flow Rate in the Dispensing-Based Process for Fabricating Tissue Scaffolds,” ASME Journal of Manufacturing Science and Engineering, 130(2), 210031-7.