DROSOPHILA BEHAVIOURAL GENETICS
, Chevrier, K., Turriff, N., Al-Tahir, Y., Shahi, D., Shaikhei Gorjan, A., Li, A.S.O., , Donà, E., Ferrari, M., Unniappan, S., (2026) Sexual identity of Akh neurons shapes Nucb1-dependent metabolic and reproductive plasticity. iScience 29(6), 116097. https://doi.org/10.1016/j.isci.2026.116097
Bernardes, L.M.M., Marquez, A.S., do Prado Mascarenhas, F.N.A., de Freitas, L.F., Ferreira, D.C., Malta, S.M., Moreira, A.S., Mendonça, T.P., Bernardo de Sousa, J.N., Silva, Í.F., et al. (2026). Acetonic extract of Saskatoon berry attenuates amyloid-associated neurotoxicity in cellular and Drosophila melanogaster Alzheimer’s disease models. Biomedicine & Pharmacotherapy 202, 119774. https://doi.org/10.1016/j.biopha.2026.119774
, Chan, Y.B., Fernandez, M.P., , , (2022) Sexually dimorphic cholinergic mechanosensory neurons regulate copulation duration and persistence. Scientific Reports. 12, 6177. https://doi.org/10.1038/s41598-022-10247-3
, Chan, Y.B., Fernandez, M.P., (2018) Characterization of the Sexually Dimorphic fruitless Neurons that Regulate Copulation Duration. Frontiers in Physiology 9, 780.
Andrews, J.C., Fernández, M.P., Yu, Q., Leary, G.P., , Kavanaugh, M.P., Kravitz, E.A., Certel, S.J. (2014) Octopamine neuromodulation regulates Gr32a-linked aggression and courtship pathways in Drosophila males. PLOS Genetics 10, e1004356.
Mundiyanapurath, S., Chan, Y.B., , Kravitz, E.A. (2009) Feminizing cholinergic neurons in a male Drosophila nervous system enhances aggression. Fly 3(3), 179-84.
BIOCHEMISTRY AND STRUCTURAL BIOLOGY
, Acquah, F.A., Mooers, B.H.M., Ferré-D’Amaré, A.R. & (2021) Engineering crystal packing in RNA structures I: Past and future strategies for engineering RNA packing in crystals. Crystal 11(8), 952 (https://doi.org/10.3390/cryst11080952)
, Li, J., Krummel, D., Kondo, Y., Roon, M., V. (2021) Engineering crystal packing in RNA-protein complexes II: A historical perspective from the structural studies of the spliceosome. Crystal 11(8), 948 (https://doi.org/10.3390/cryst11080948)
, Patnaik, D., , Bishop, J., , , , , , Murphy, M., Tsai, L-H., Haggarty, S.*, Leung, A.K.* (2020) Identification and Mechanistic Characterization of a Novel Peptide Inhibitor of Glycogen Synthase Kinase (GSK3) Derived from the Disrupted in Schizophrenia 1 (DISC1) Protein. ACS Chem Neurosci. 11, 4128-4138.
Leung, A.K., Ramesh, N., Vogel, C., Unniappan, S.* (2019) Nucleobindins and Encoded Peptides: From Cell Signaling to Physiology. In Advances in Protein Chemistry and Structural Biology, Donev, R., Ed. Elsevier, Acaedmic Press: Vol. 116, p 91-133.
Li, J.*, Leung, A.K., Kondo, Y., Oubridge, C. and Nagai, K.* (2016) Re-refinement of the spliceosomal U4 snRNP core-domain structure. Acta Cryst. D72, 131-146. (Impact Factor: 7.652, Number of Citation: 13)
Leung, A.K., Nagai, K. and Li, J. (2011) Crystal Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis. Nature 473, 536-539.
Leung, A.K., Kambach, C., Kondon, Y., Kampmann, M., Jinek, M. and Nagai, K. (2010) Use of RNA Tertiary Interaction Modules for the Crystallisation of the Spliceosomal snRNP Core Domain. J. Mol. Biol 402, 154-164.
Oubridge, C., Krummel, D.A., Leung, A.K., Li, J., Nagai, K. (2009) Interpreting a low resolution map of human U1 snRNP using anomalous scatterers. Structure 17(7), 930-8.
Pomeranz Krummel, D.A., Oubridge, C., Leung, A.K., Li, J., Nagai K. (2009) Crystal structure of human spliceosomal U1 snRNP at 5.5 Å resolution. Nature 458(7237), 475-80.
Reynolds, R.C., Campbell, S.R., Fairchild, R.G., Kisliuk, R.L., Micca, P.L., Queener, S.F., Riordan, J.M., Sedwick, W.D., Waud, W.R., Leung, A.K., Dixon, R.W., Suling, W.J., Borhani, D.W. (2007) Novel boron containing, nonclassical antifolates: synthesis and preliminary biological and structural evaluation. J. Med. Chem. 50, 3283-3289.
Leung, A.K. and Nagai, K. (2005) Gemin 6 and 7 lend a hand to snRNP assembly. Structure, 13(6), 833-4.
Leung, A.K., White, LE., Ross, LJ, Reynolds, RC, DeVito, JA, Borhani, DW. (2004) Structure of Mycobacterium tuberculosis FtsZ Reveals Unexpected, G Protein-like Conformational Switches J Mol Biol., 342, 953-70.
Borhani, D.W., Calderwood, D.J., Friedman, M.M., Hirst, G.C., Li, B., Leung, A.K., McRae, B., Ratnofsky, S., Ritter, K. and Waegell, W. (2004) A potent, orally active inhibitor of lck with efficacy in a model of transplant rejection Bioorganic & Medicinal Chemistry Letters, 14(10), 2613-2616.
Burk, D.L., Hon, W.-C., Leung, A.K., and Berghuis, A.M. (2001) Structural analyses of nucleotide binding to an aminoglycoside phosphotransferase. Biochemistry, 40, 8756-64.
Leung, A.K., Duewel, H.S., Honek, J. F., and Berghuis, A.M. (2001) Crystal structure of the lytic transglycosylase from bacteriophage lambda in complexed with hexa-N-acetylchitohexaose. Biochemistry, 40, 5665 -5673.
Leung, A.K., White, E.L., Ross, L.J., and Borhani, D.W. (2000) Crystallization of the Mycobacterium tuberculosis cell-division protein FtsZ. Acta Cryst., D56, 1634-1637.
Leung, A.K., Park, M.M.V., and Borhani, D.W. (1999) An improved method for protein crystal density measurements. J. Appl. Cryst., 32, 1006-1009.
Patent
US 7,400,979 B2 (15-JUL-2008) Borhani, David W.; Calderwood, David; Dixon, Richard W.; Hirst, Gavin C.; Hrnciar, Peter; Loew, Andreas; Leung, Adelaine; Ritter, Kurt. “Method of identifying inhibitors of Lck.” (Abbott Laboratories, Inc.). PCT Int. Appl. WO 2003/020880 A2 (Filed 2-AUG-2002, Publ. 13-MAR-2003); US Appl. US 2002 10/212,346 A (Filed 5-AUG-2002, Publ. 18-SEP-2003). Priority: U.S. Provisional Appl. No. 60/310,051 filed 3-AUG-2001.