2018 - 2010
Pedras, M. S. C.;* To, Q. H. 2018 Synthesis of stable isotope–labeled nasturlexins and potential precursors to probe biosynthetic pathways of cruciferous phytoalexins. Journal of Labelled Compounds and Radiopharmaceuticals, 1–13. https://doi.org/10.1002/jlcr.3591.
Pedras, M. S. C.;* Abdoli, A. 2017. Discovery of inhibitors of brassinin oxidase based on quinoline and isoquinoline scaffolds: design, synthesis and antifungal activity. Molecules, 22, 1345; doi:10.3390/molecules22081345.
Pedras, M. S. C.* Abdoli, A. 2017. Pathogen inactivation of cruciferous phytoalexins: detoxification reactions, enzymes and inhibitors. RSC Advances, 7, 23633-23646.
Pedras, M. S. C.;* To, Q. H. 2017. Defense and signalling metabolites of the crucifer Erucastrum canariense: synchronized abiotic induction of phytoalexins and galactosyl-oxylipins. Phytochemistry, 139 18-24.
Pedras, M. S. C.;* Abdoli, A. 2017. Biotransformation of rutabaga phytoalexins by the fungus Alternaria brassicicola: unveiling the first hybrid metabolite derived from a phytoalexin and a fungal polyketide. Bioorganic & Medicinal Chemistry, 25, 557–567.
Pedras, M. S. C.;* Park, M. R. 2016. The biosynthesis of brassicicolin A in the phytopathogen Alternaria brassicicola. Phytochemistry, 132, 26-32.
Pedras, M. S. C.; To, Q. H. 2016. Unveiling the first indole-fused thiazepine: structure and synthesis of the cruciferous phytoalexin cyclonasturlexin.Chemical Communications, 52, 5880-5883.
Pedras, M. S. C.; To, Q. H.; Schatte, G. 2016. Divergent reactivity of an indole glucosinolate yields Lossen or Neber rearrangement products: the phytoalexin rapalexin A or a unique β-D-glucopyranose fused heterocycle.Chemical Communications, 52, 2505-2508.
Pedras, M. S. C.; Alavi, M.; To, Q. H. 2015. Expanding the nasturlexin family: nasturlexins C and D and their sulfoxides are phytoalexins from the crucifers Barbarea vulgaris and B. verna. Phytochemistry, 118 131-138.
Pedras, M. S. C.; Park, M. R. 2015. Metabolite diversity in the plant pathogen Alternaria brassicicola: factors affecting production of brassicicolin A, depudecin, phomapyrone A and other metabolites. Mycologia, 107, 1138-1150.
Pedras, M. S. C.; Yaya, E. E. 2015. Plant chemical defenses: Are all constitutive antimicrobial metabolites phytoanticipins- Natural Products Communications, 9, 209-216 (INVITED REVIEW).
Pedras, M. S. C.; To, Q. H. 2015. Non-indolyl cruciferous phytoalexins: Nasturlexins and tridentatols, a striking convergent evolution of defenses in terrestrial plants and marine animals- Phytochemistry, 113, 57-63.
Pedras, M. S. C.; Minic, Z.; Abdoli, A. 2014. The phytoalexin camalexin induces fundamental changes in the proteome of Alternaria brassicicola different from those caused by brassinin. Fungal Biology, 118, 83-93.
Pedras, M. S. C. 2014. Chemistry and biology of the cruciferous phytoalexins brassinin and cyclobrassinin. The Natural Products Journal, 4, 166-172 (INVITED REVIEW).
Grubb, C. D.; Zipp, B.; Kopycki, J.; Schubert, M.; Quint, M.; Lim, E.-K.; Bowles, D.; Pedras, M. S. C.; Abel, S. 2014. Comparative analysis of Arabidopsis UGT74 glucosyltransferases reveals a special role of UGT74C1 in glucosinolate biosynthesis. The Plant Journal, 79, 92-105.
Pedras, M. S. C.; Yaya, E. E. 2014. Tenualexin, other phytoalexins and indole glucosinolates from wild cruciferous species. Chemistry & Biodiversity, 11, 910-918.
Pedras, M. S. C.; Minic, Z.; Abdoli, A. 2014. The phytoalexin camalexin induces fundamental changes in the proteome of Alternaria brassicicola different from those caused by brassinin.Fungal Biology, 118, 83-93.
Pedras, M. S. C.; Minic, Z. 2014. The phytoalexins brassilexin and camalexin inhibit cyclobrassinin hydrolase, a unique enzyme from the fungal pathogenAlternaria brassicicola. Bioorganic & Medicinal Chemistry, 22, 459-467.
Pedras, M. S. C.; Abdoli, A. 2013. Metabolism of the phytoalexins camalexins, their bioisosteres and analogues in the plant pathogenic fungus. Alternaria brassicicola. Bioorganic & Medicinal Chemistry, 21 4541-4549.
Pedras, M. S. C. 2013. Metabolism and detoxification of phytoalexins from crucifers and application to the control of fungal plant pathogens. Biotechnology of Crucifers, S. Gupta, ed., Springer, 151-171.
Pedras, M. S. C.; Yaya, E. E. 2013v. Dissecting metabolic puzzles through isotope feeding: novel amino acid in the biosynthetic pathway of the phytoalexins rapalexin A and isocyalexin A. Organic & Biomolecular Chemistry, 11, 1149-1166.
Pedras, M. S. C.; Abdoli, A; Chumala, P. B.; Saha, P.; Schatte, G. 2013v.Unprecedented spirocyclization of 3-methyleneindoline-2-thiones during hydrolysis of the phytoalexin cyclobrassinin. Bioorganic & Medicinal Chemistry Letters, 23, 484-487.
Pedras, M. S. C.; Sarma-Mamillapalle, V. K. 2012v. Metabolism and metabolites of dithiocarbamates in Leptosphaeria maculans, Journal of Agricultural & Food Chemistry, 60, 7792-7798.
Pedras, M. S. C.; Sarma-Mamillapalle, V. K. 2012v. The phytoalexins rapalexin A, brussalexin A and erucalexin: chemistry and metabolism in Leptosphaeria maculans. Bioorganic & Medicinal Chemistry, 20, 3991-3996.
Pedras, M. S. C.; Abdoli, A; Chumala, P. B.; Saha, P.; Schatte, G. 2012. Unprecedented spirocyclization of 3-methyleneindoline-2-thiones during hydrolysis of the phytoalexin cyclobrassinin. Bioorganic & Medicinal Chemistry Letters, 10.1016/j.bmcl.2012.11.042.
Pedras, M. S. C.; Sarma-Mamillapalle, V. K. 2012. Metabolism and metabolites of dithiocarbamates in Leptosphaeria maculans. Journal of Agricultural & Food Chemistry, 60, 7792-7798.
Pedras, M. S. C.; Yaya, E. E. 2012. The first isocyanide of plant origin expands functional group diversity in cruciferous phytoalexins: synthesis, structure and bioactivity of isocyalexin A. Organic & Biomolecular Chemistry, 10, 3613-3616.
Pedras, M. S. C.; Khallaf, I. 2012. Molecular interactions of the phytotoxins destruxin B and sirodesmin PL with crucifers and cereals: metabolism and elicitation of plant defenses. Phytochemistry, 77, 129-139.
Pedras, M. S. C.; Sarma-Mamillapalle, V. K. 2012. The phytoalexins rapalexin A, brussalexin A and erucalexin: chemistry and metabolism in Leptosphaeria maculans. Bioorganic & Medicinal Chemistry, 20, 3991-3996.
Pedras, M. S. C.; Minic, Z. 2012. Differential protein expression in response to the phytoalexin brassinin identifies molecular targets in the phytopathogenic fungus Alternaria brassicicola. Molecular Plant Pathology, 13, 483-493.
Pedras, M. S. C.; Minic, Z.; Hossain, S. 2012. Discovery of inhibitors and substrates of brassinin hydrolase: Probing selectivity with dithiocarbamate bioisosteres. Bioorganic & Medicinal Chemistry, 20, 225-233.
Pedras, M. S. C.; Hossain, S. 2011. Interaction of phytoanticipins with plant fungal pathogens: indole glucosinolates are not metabolized but the corresponding desulfo-derivatives and nitriles are. Phytochemistry, 72, 2308-2316.
Pedras, M. S. C.; Yaya, E. E.; Glawischnig, E. 2011. The phytoalexins from cultivated and wild crucifers: Chemistry and biology. Natural Product Reports, 28, 1381-1405.
Pedras, M. S. C.; Chumala, P. B. 2011. Maculansins, cryptic phytotoxins from blackleg fungi. Natural Product Communications, 6, 617-620.
Pedras, M. S. C.; Minic, Z.; Sarma-Mamillapalle, V. K. 2011. Brassinin oxidase mediated transformation of the phytoalexin brassinin: Structure of the elusive co-product, deuterium isotope effect and stereoselectivity.Bioorganic & Medicinal Chemistry, 19, 1390-1399.
Pedras, M. S. C.; Hossain S.; Snitynsky, R. B. 2011. Detoxification of cruciferous phytoalexins in Botrytis cinerea: spontaneous dimerization of a camalexin metabolite. Phytochemistry, 72, 199-206.
Pedras, M. S. C. 2011. Fungal attack and cruciferous defenses: tricking plant pathogens. Recent Advances in Phytochemistry, 41, 127-139.
Pedras, M. S. C.; Minic, Z.; Devi, P. T.; Bhaskar, V.; Montaut, S. 2010. Indolyl-3-acetaldoxime dehydratase from the phytopathogenic fungus Sclerotinia sclerotiorum: Purification, characterization, and substrate specificity.Phytochemistry, 71, 1952-1962.
Pedras, M. S. C.; Yaya, E. E.; Hossain S. 2010. Unveiling the phytoalexin biosynthetic puzzle in salt cress: Unprecedented incorporation of glucobrassicin into wasalexins A and B. Organic & Biomolecular Chemistry, 8, 5150-5158.
Pedras, M. S. C.; Snitynsky, R. B. 2010. Impact of cruciferous phytoalexins on the detoxification of brassilexin by the blackleg fungus pathogenic to brown mustard. Natural Product Communications, 5, 883-888.
Pedras, M. S. C.; Yaya, E. E. 2010. Phytoalexins from Brassicaceae: news from the front. Phytochemistry, 71, 1191-1197.
Pedras, M. S. C.; Minic, Z.; Sarma-Mamillapalle, V.; Suchy, M. 2010. Discovery of inhibitors of brassinin oxidase based on the brassilexin and wasalexin scaffolds. Bioorganic & Medicinal Chemistry, 18, 2456-2463.
Pedras, M. S. C.; Zheng, Q. A. 2010. Metabolic responses of Thellungiella halophila/salsuginea to biotic and abiotic stresses: Metabolite profiles and quantitative analyses. Phytochemistry, 71, 581-589.
Pedras, M. S. C.; Zheng, Q. A. 2010. Development and Modification of Bioactivity - Products: The Chemistry of Arabidopsis thaliana. In Comprehensive Natural Products II Chemistry and Biology; Mander, L., Lui, H.-W., Eds.; Elsevier: Oxford, 2010; volume 3, pp. 1297-1315. (INVITED REVIEW).BC
2009 - 2000
Pedras, M. S. C.; Zheng, Q. A.; Shatte, G.; Adio, A. M. 2009. Photochemical dimerization of wasalexins in UV-irradiated Thellungiella halophila and in vitro generates unique cruciferous phytoalexins. Phytochemistry, 70, 2010-2016.
Pedras, M. S. C.; Minic, Z.; Sarma-Mamillapalle, V. 2009. Substrate specificity and inhibition of brassinin hydrolases, detoxifying enzymes from the plant pathogens Leptosphaeria maculans and Alternaria brassicicola. FEBS Journal, 276, 7412-7428.
Pedras, M. S. C.; Yu, Y. 2009. Phytotoxins, elicitors and other secondary metabolites from phytopathogenic blackleg fungi: structure, phytotoxicity and biosynthesis. Natural Product Communications, 4, 1291-1304 (REVIEW).
Pedras, M. S. C.; Okinyo-Owiti, D. P.; Thoms, K.; Adio, A. M. 2009. The biosynthetic pathway of crucifer phytoalexins and phytoanticipins: de novoincorporation of deuterated tryptophans and quasi-natural compounds.Phytochemistry, 70, 1129-1138.
120. Pedras, M. S. C.; Zheng, Q. A. 2009. Phytoalexins. In Biology and Breeding of Crucifers, CRC Press, Ed. Gupta, S. K., pp. 249-259 (INVITED REVIEW).
Pedras, M. S. C.; Minic, Z.; Sarma-Mamillapalle, V. 2009. Synthetic inhibitors of the fungal detoxifying enzyme brassinin oxidase based on the phytoalexin camalexin scaffold. Journal of Agricultural & Food Chemistry, 57, 2429-2435.
Pedras, M. S. C.; Chumala, P. B.; Jin, W.; Islam, M. S.; Hauck, D. W. 2009. The phytopathogenic fungus Alternaria brassicicola: Phytotoxin production and phytoalexin elicitation. Phytochemistry, 70, 394-402.
Pedras, M. S. C.; Yu, Y. 2009. Mapping the sirodesmin PL biosynthetic pathway: a remarkable intrinsic steric deuterium isotope effect on a BH NMR chemical shift determines β-proton exchange in tyrosine. Canadian Journal of Chemistry 87, 556-562.
Sexton, A. C.; Minic, Z.; Cozijnsen, A. C.; Pedras, M. S. C.; Howlett, B. J. 2009. Cloning, purification and characterization of brassinin glucosyltransferase, a phytoalexin-detoxifying enzyme from the plant pathogen Sclerotinia sclerotiorum. Fungal Genetics and Biology, 46, 201-209.
Pedras, M. S. C.; Yu, Y. 2009. Salt stress induces production of melanin related metabolites in the phytopathogenic fungus Leptosphaeria maculans. Natural Products Communications, 4, 53-58.
Pedras, M. S. C.; Yu, Y. 2008. Structure and biological activity of maculansin A, a phytotoxin from the phytopathogenic fungus Leptosphaeria maculans.Phytochemistry, 69, 2966-2971.
Pedras, M. S. C.; Zheng, Q. A.; Strelkov, S. 2008. Metabolic changes in roots of the oilseed canola infected with the biotroph Plasmodiophora brassicae: phytoalexins and phytoanticipins. Journal of Agricultural & Food Chemistry,56, 9949-9961.
Pedras, M. S. C.; Yu, Y. 2008. Stress-driven discovery of metabolites from the fungal plant pathogen Leptosphaeria maculans: structure and activity of leptomaculins. Bioorganic & Medicinal Chemistry, 16, 8063-8071.
Pedras, M. S. C.; Gadagi, R. S.; Zheng, Q. A.; Rimmer, S. R. 2008. Selective elicitation of the phytoalexin rutalexin in rutabaga and turnip roots by a biotrophic plant pathogen. Natural Product Communications, 3, 1239-1243.
Pedras, M. S. C.; Minic, Z.; Jha, M. 2008. Brassinin oxidase, a fungal detoxifying enzyme to overcome a plant defense: purification, characterization and inhibition. FEBS Journal, 275, 3691-3705.
Pedras, M. S. C. 2008. The chemical ecology of crucifers and their fungal pathogens: boosting plant defenses and inhibiting pathogen invasion. The Chemical Record, 8, 109-115. (INVITED REVIEW)
Pedras, M. S. C.; Adio, A. M. 2008. Phytoalexins and phytoanticipins from the wild crucifers Thellungiella halophila and Arabidopsis thaliana: rapalexin A,wasalexins and camalexin. Phytochemistry, 69, 889-893.
Pedras, M. S. C.; Okinyo, D. P. O. 2008. Remarkable incorporation of the first sulfur containing indole derivative: Another piece in the puzzle of crucifer phytoalexins. Organic & Biomolecular Chemistry, 6, 51-54.
Pedras, M. S. C.; Zheng, Q. A.; Gadagi, R. S.; Rimmer, S. R. 2008. Phytoalexins and polar metabolites from the oilseeds canola and rapeseed: Differential metabolic responses to the biotroph Albugo candida and to abiotic stress.Phytochemistry, 69, 894-910.
Pedras, M. S. C.; Jha, M.; Minic, Z.; Okeola, O. G. 2007. Isosteric probes provide structural requirements essential for detoxification of the phytoalexin brassinin by the fungal pathogen Leptosphaeria maculans. Bioorganic & Medicinal Chemistry, 15, 6054-6061.
Pedras, M. S. C.; Hossain, M. 2007. Design, synthesis, and evaluation of potential inhibitors of brassinin glucosyl transferase, a phytoalexin detoxifying enzyme from Sclerotinia sclerotiorum. Bioorganic & Medicinal Chemistry,15, 5981-5996.
Pedras, M. S. C.; Gadagi, R. S.; Jha, M.; Sarma-Mamillapalle, V. K. 2007. Detoxification of the phytoalexin brassinin by isolates of Leptosphaeria maculans pathogenic on brown mustard involves an inducible hydrolase.Phytochemistry, 68, 1572-1578.
Pedras, M. S. C.; Chumala, P. B.; Yu, Y. 2007. The phytopathogenic fungiLeptosphaeria maculans and L. biglobosa: chemotaxonomical characterization of isolates and metabolite production in different culture media. Canadian Journal of Microbiology, 53, 364-371.
Pedras, M. S. C.; Zheng, Q. A.; Sarwar, M. G. 2007. Efficient synthesis of brussalexin A, a remarkable phytoalexin from Brussels sprouts. Organic & Biomolecular Chemistry, 5, 1167-1169.
Pedras, M. S. C.; Zheng, Q. A.; Sarma-Mamillapalle, V. K. 2007. The Phytoalexins from Brassicaceae: structure, biological activity, synthesis and biosynthesis. Natural Product Communications, 2, 319-330. (INVITED REVIEW)
Pedras, M. S. C.; Zheng, Q. A.; Gadagi, R. S. 2007. The first naturally occurring aromatic isothiocyanates, rapalexins A and B, are cruciferous phytoalexins.Chemical Communications, 368 - 370.
Pedras, M. S. C.; Suchy, M. 2006. Metabolism of the crucifer phytoalexins wasalexins A and B in the plant pathogenic fungus Leptosphaeria maculans. Organic and Biomolecular Chemistry, 4, 3526 - 3535.
Pedras, M. S. C.; Adio, A. M.; Suchy, M.; Okinyo, D. P. O; Zheng, Q. A.; Jha, M.; Sarwar, M. G. 2006. Detection, characterization and identification of crucifer phytoalexins using high-performance liquid chromatography diode array and electrospray ionization mass spectrometry. Journal of Chromatography A, 1133, 172-183.
Pedras, M. S. C.; Sarwar, M. G.; Suchy, M.; Adio, A. M. 2006. The phytoalexins from cauliflower, caulilexins A, B and C: isolation, structure determination, syntheses and antifungal activity. Phytochemistry, 67, 1503-1509.
Pedras, M. S. C.; Hossain, M. 2006. Metabolism of crucifer phytoalexins inSclerotinia sclerotiorum: detoxification of strongly antifungal compounds involves glucosylation. Organic & Biomolecular Chemistry, 4, 2581-2590.
Pedras, M. S. C.; Okinyo, D. P. O. 2006. En route to erucalexin: a unique rearrangement in the crucifer phytoalexin biosynthetic pathway. Chemical Communications, 1848-1850.
Pedras, M. S. C.; Jha, M. 2006. Toward the control of Leptosphaeria maculans: design, syntheses, biological activity and metabolism of potential detoxification inhibitors of the crucifer phytoalexin brassinin. Bioorganic & Medicinal Chemistry, 14, 4958-4979.
Pedras, M. S. C.; Chumala, P. B. 2006. Peptides and depsipeptides from plant pathogenic fungi. Handbook of Biologically Active Peptides, Abba Kastin, Ed., Elsevier, pp 1640. ISBN: 0-12-369442-6 (INVITED REVIEW).
Pedras, M. S. C.; Suchy, M.; Ahiahonu, P. W. K. 2006. Unprecedented chemical structure and biomimetic synthesis of erucalexin, a phytoalexin from the wild crucifer Erucastrum gallicum. Organic & Biomolecular Chemistry, 4, 691-697.
Pedras, M. S. C.; Okinyo, D. P. O. 2006. Syntheses of perdeuterated indoles and derivatives as probes for the biosyntheses of crucifer phytoalexins.Journal of Labelled Compounds & Radiopharmaceuticals, 49, 33-45.
Pedras, M. S. C.; Suchy, M. 2006. Design, synthesis, evaluation and antifungal activity of inhibitors of brassilexin detoxification in the plant pathogenic fungus Leptosphaeria maculans. Bioorganic & Medicinal Chemistry, 14, 714-723.
Pedras, M. S. C.; Jha, M.; Okeola, O. G. 2005. Camalexin Induces Detoxification of the Phytoalexin Brassinin in the Plant Pathogen Leptosphaeria maculans.Phytochemistry, 66, 2609-2616.
Pedras, M. S. C.; Yu, Y.; Liu, J.; Tandron-Moya, Y. A. 2005. Metabolites produced by the phytopathogenic fungus Rhizoctonia solani: isolation, chemical structure determination, syntheses and bioactivity. Zeitschrift fur Naturforschung C, 60c, 717-722.
Pedras, M. S. C.; Suchy, M. 2005. Detoxification pathways of the phytoalexins brassilexin and sinalexin in Leptosphaeria maculans: isolation and synthesis of the elusive intermediate 3-formylindolyl-2-sulfonic acid. Organic & Biomolecular Chemistry, 3, 2002-2007.
Pedras, M. S. C.; Chumala, P. B.; Uppala, V. 2005. New sesquiterpenic phytotoxins establish unprecedented relationship between blackleg fungal isolates.Bioorganic & Medicinal Chemistry, 13, 2469-2475.
Pedras, M. S. C.; Jha, M. 2005. Concise syntheses of the cruciferous phytoalexins brassilexin, sinalexin, wasalexins, and analogs: expanding the scope of the Vilsmeier formylation. Journal of Organic Chemistry, 70, 1828-1834.
Pedras, M. S. C.; Ahiahonu, P. W. K. 2005. Metabolism and detoxification of phytoalexins and analogs by phytopathogenic fungi. Phytochemistry, 66, 391-411 (REVIEW).
Pedras, M. S. C.; Chumala, P. B. 2005. Phomapyrones from new blackleg isolates: isolation, structure determination, biological activity and biosyntheses.Phytochemistry, 64, 81-87.
Pedras, M. S. C.; Chumala, P. B.; Quail, J. W. 2004. Chemical mediators: the remarkable structure and host-selectivity of depsilairdin, a sesquiterpenic depsipeptide containing a new amino acid. Organic Letters, 6, 4615-4617.
Pedras, M. S. C.; Hossain, M.; Sarwar, M. G.; Montaut, S. 2004. Determination of the enantiomeric purity of the phytoalexins spirobrassinins by 1H NMR using chiral solvation. Bioorganic & Medicinal Chemistry Letters, 14, 5469-5471.
Pedras, M. S. C. 2004. Prospects for controlling plant fungal diseases: alternatives based on chemical ecology and biotechnology. Canadian Journal of Chemistry, 82, 1329-1335. (Canadian Society for Chemistry, Clara Benson award lecture, INVITED).
Pedras, M. S. C.; Ahiahonu, P. W. K.; Hossain, M. 2004. Detoxification of the cruciferous phytoalexin brassinin in Sclerotinia sclerotiorum requires an inducible glucosyltransferase. Phytochemistry, 65, 2685-2694.
Pedras, M. S. C.; Ahiahonu, P. W. K. 2004. Phytotoxin production and phytoalexin elicitation by the phytopathogenic fungus Sclerotinia sclerotiorum. Journal of Chemical Ecology, 30, 2163 - 2179.
Gardiner, D. M.; Cozijnsen, A. J.; Wilson, L. M.; Pedras, M. S. C.; Howlett, B. J. 2004. The sirodesmin biosynthetic gene cluster of the plant pathogenic fungus Leptosphaeria maculans. Molecular Microbiology, 53, 1307-1318.
Pedras, M. S. C.; Montaut, S.; Suchy, M. 2004. New phytoalexins from rutabaga: structures, syntheses, biosyntheses, and biological activity. Journal of Organic Chemistry, 69, 4471-4476.
Pedras, M. S. C.; Liu, J. 2004. Designer phytoalexins: probing camalexin detoxification pathways in the phytopathogen Rhizoctonia solani. Organic and Biomolecular Chemistry, 2, 1070-1076.
Pedras, M. S. C.; Montaut, S. 2004. The biosynthesis of crucifer phytoalexins: unprecedented incorporation of a 1-methoxyindolyl precursor. Chemical Communications, 452-453.
Idnurm, A.; Taylor, J. L. Pedras, M. S. C.; Howlett, B. J. 2003. Small scale functional genomics of the blackleg fungus Leptosphaeria maculans: analysis of a 38 kb region. Australasian Plant Pathology, 32 (4): 511-519.
Pedras, M. S. C.; Jha, M.; Ahiahonu, P. W. K. 2003. The synthesis and biosynthesis of phytoalexins produced by cruciferous plants. Current Organic Chemistry 7, 1635-1647 (REVIEW).
Pedras, M. S. C.; Montaut, S.; Zaharia, I. L.; Gai, Y.; Ward, D. E. 2003. Biotransformation of the Host-selective Toxin Destruxin B by Wild Crucifers: Probing a Detoxification Pathway. Phytochemistry, 64, 957-963.
Pedras, M. S. C.; Chumala, P. B.; Suchy, M. 2003. Phytoalexins from Thlaspi arvense, a wild crucifer resistant to virulent Leptosphaeria maculans: structures, syntheses and antifungal activity. Phytochemistry, 64, 949-956.
Pedras, M. S. C.; Montaut, S. 2003. Probing metabolic pathways in fungal pathogens of crucifers: biotransformation of indole-3-acetaldoxime, 4-hydroxyphenylacetaldoxime, and their metabolites. Bioorganic & Medicinal Chemistry, 11, 3115-3120.
Pedras, M. S. C.; Ismail, N.; Quail, W.; Boyetchko, S. 2003. Structure, chemistry, and biological activity of pseudophomins A and B, a class of cyclic lipodepsipeptides isolated from the biocontrol bacteriumPseudomonas fluorescens. Phytochemistry, 62, 1105 - 1114.
Pedras, M. S. C.; Ahiahonu, P. W. K. 2002. Probing the phytopathogenic stem rot fungus with phytoalexins and analogs: unprecedented glucosylation of camalexin and 6-methoxycamalexin. Bioorg. Med. Chem., 10, 3307-3312.
Pedras, M. S. C.; Nycholat, C. M.; Montaut, S.; Xu, Y.; Khan, A. K. 2002. Chemical defenses of crucifers: elicitation and metabolism of phytoalexins and indole-3-acetonitrile in brown mustard and turnip. Phytochemistry, 59, 611-625.
Pedras, M. S. C.; Zaharia, I. L.; Ward, D. E. 2002. The destruxins: synthesis, biosynthesis, biotransformation, and biological activity. Phytochemistry, 59, 579-596. (REVIEW)
Ward, D. E.; Gai, Y.; Lazny, R.; Pedras, M. S. C. 2001. Probing host-selective phytotoxicity: synthesis of natural analogs of the host-selective toxin destruxin B. Journal of Organic Chemistry, 66,7832-7840.
Pedras, M. S. C.; Biesenthal, C. J. 2001. Secondary metabolites from the phytopathogenic fungus Phoma lingam: detection, isolation, structure determination, and phytotoxicity of unusual dioxopiperazines.Phytochemistry, 58, 905-909.
Pedras, M. S. C.; Montaut, S.; Xu, Y; Khan, A. Q.; Loukaci, A. 2001. Assembling the biosynthetic puzzle of crucifer metabolites: indole-3-acetaldoxime is incorporated efficiently into phytoalexins but glucobrassicin is not.Chemical Communications, 1572-1573.
Pedras, M. S. C. 2001. Phytotoxins from fungi causing blackleg disease on crucifers: isolation, structure determination, detection, and phytotoxic activity. Recent Research Developments in Phytochemistry, 5, 109-117 (REVIEW).
Howlett B. J.; Idnurm A.; Pedras M. S. C. 2001. Leptosphaeria maculans the causal agent of blackleg disease of brassicas. Fungal Genetics and Biology, 33, 1-14 (REVIEW).
Pedras, M. S. C.; Zaharia, I. L. 2001. Unprecedented Vilsmeier formylation: expedient synthesis of the cruciferous phytoalexin sinalexin and discovery of a new heteroaromatic ring system. Organic Letters, 3, 1213-1216.
Pedras, M. S. C.; Zaharia, I.L.; Gai, Y.; Zhou, Y.; Ward, D. E. 2001. In plantasequential hydroxylation and glycosylation of a fungal phytotoxin: avoiding cell death and overcoming the fungal invader. Proceedings of the National Academy Sciences, USA, 98 747-752.
Pedras, M. S. C.; Zaharia, I. L. 2000. Sinalbins A and B, phytoalexins fromSinapis alba: elicitation, isolation, and synthesis. Phytochemistry, 55, 213-216.
Pedras, M. S. C.; Biesenthal, C. J. 2000. Vital staining of plant cell suspension cultures: evaluation of the phytotoxic activities of the phytotoxins phomalide and destruxin B. Plant Cell Reports, 19, 1135-1138.
Pedras, M. S. C.; Biesenthal, C. J. 2000. HPLC Analyses of cultures of Phomaspecies: differentiation among groups and species through secondary metabolite profiles. Canadian Journal of Microbiology, 46, 685-691.
Pedras, M. S. C.; Biesenthal, C. J.; Zaharia, I. L. 2000. Comparison of the phytotoxic activity of the phytotoxin destruxin b and four natural analogs.Plant Science, 156, 185-192.
Pedras, M. S. C.; Okanga F. I. 2000. Metabolism of Analogs of the Phytoalexin Brassinin by Plant Pathogenic Fungi. Canadian Journal of Chemistry, 78, 338-346.
Pedras, M. S. C.; Okanga, F. I.; Zaharia, I. L; Khan, A. Q. 2000. Phytoalexins from crucifers: synthesis, biosynthesis, and biotransformation.Phytochemistry, 53, 161-176. (REVIEW).
Pedras, M. S. C.; Khan, A. Q. 2000. Biotransformation of the phytoalexin camalexin by the root phytopathogen Rhizoctonia solani. Phytochemistry, 53, 59-69.
1999 - 1990
Pedras, M. S. C.; Erosa-Lopez, C. C.; Quail, J. W.; Taylor, J. L. 1999. Phomalairdenone, a new host-selective phytotoxin from a virulent type of the blackleg fungus Phoma lingam. Bioorganic & Medicinal Chemistry Letters, 9, 3291-3294.
Pedras, M. S. C.; Zaharia, I.L.; Gai, Y.; Smith, K. C.; Ward, D. E. 1999. Metabolism of the host-selective toxins destruxin b and homodestruxin b: probing a plant disease resistance trait. Organic Letters, 1, 1655-1658.
Pedras, M. S. C. ; Sorensen, J. L.; Okanga, F. I.; Zaharia, I. L. 1999. Wasalexins A and B, new phytoalexins from wasabi: isolation, synthesis, and antifungal activity. Bioorganic & Medicinal Chemistry Letters, 9, 3015-3020.
Pedras, M. S. C.; Okanga, F. I. 1999. Strategies of cruciferous pathogenic fungi: detoxification of the phytoalexin cyclobrassinin by mimicry. Journal of Agricultural & Food Chemistry, 47, 1196-1202.
Ward, D. E.; Vazquez, A.; Pedras, M. S. C. 1999. Probing host-selective phytotoxicity: synthesis and biological activity of phomalide, isophomalide and dihydrophomalide. Journal of Organic Chemistry, 67, 1657-1666.
Pedras, M. S. C.; Khan, A.Q.; Taylor, J. L. 1998. The phytoalexin camalexin is not metabolized by Phoma lingam, Alternaria brassicae, or phytopathogenic bacteria. Plant Science, 139, 1-8.
Pedras, M. S. C.; Loukaci, A.; Okanga F. I. 1998. The Cruciferous Phytoalexins Brassinin and Cyclobrassinin Are Intermediates in The Biosynthesis of Brassilexin. Bioorganic & Medicinal Chemistry Letters, 8, 3037-3038.
Pedras, M. S. C.; Okanga, F. I . 1998. A Convenient Synthesis of the Cruciferous Phytoalexins Brassicanal A and Brassilexin by Mimicry of a Fungal Detoxification Pathway. Chemical Communications, 1565-1566.
Pedras, M. S. C.; Sorensen, J. L. 1998. Phytoalexin Accumulation and Production of Antifungal Compounds by the Crucifer Wasabi. Phytochemistry, 49, 1959-1965.
Pedras, M. S. C. 1998. Phytoalexins from crucifers: mimicking or overcoming plant chemical defenses- Recent Research Developments in Phytochemistry, 2, 259-267. (REVIEW)
Pedras, M. S. C.; Smith, K. C.; Taylor, J. L. 1998. Production of a 2,5-dioxopiperazine by a new isolate type of the blackleg fungus Phoma lingam. Phytochemistry, 49, 1575-1577.
Pedras, M. S. C.; Biesenthal, C. J. 1998. Production of the host-selective toxin phomalide by isolates of Leptosphaeria maculans and its correlation with sirodesmin PL production. Canadian Journal of Microbiology 44, 547-553.
Pedras, M. S. C. 1998. Towards an Understanding and Control of Plant Fungal Diseases in Brassicaceae, Recent Research Developments in Agricultural and Food Chemistry, 2, 513-532 (REVIEW).
Pedras, M. S. C.; Okanga, F. I. 1998. Probing the phytopathogenic blackleg fungus with a phytoalexin homolog. Journal of Organic Chemistry, 63, 416-417.
Pedras, M. S. C.; Okanga, F. I. 1998. Strategies of Fungal Pathogens: Detoxification of a Cruciferous Phytoalexin by Mimicry. Chemical Communications, 67-68.
Pedras, M. S. C.; Smith, K. C. 1997. Sinalexin, a phytoalexin from white mustard elicited by destruxin B and Alternaria brassicae, Phytochemistry, 46, 833-837.
Pedras, M. S. C.; Khan, A. Q. 1997. Unprecedented Detoxification of the Phytoalexin Camalexin by a Root Rot Pathogen, Bioorganic & Medicinal Chemistry Letters, 7, 2255-2260.
Pedras, M. S. C.; Khan, A. Q.; Smith, K. C.; Stettner, S. L. 1997. Preparation, biotransformation, and antifungal activity of methyl benzyldithiocarbamates. Canadian Journal of Chemistry, 75, 825-828.
Pedras, M. S. C. 1997. Determination of the absolute configuration of the fragments composing phomalide. Canadian Journal of Chemistry, 75, 314-317.
Ward, D. E.; Lazny, R.; Pedras, M. S. C. 1997. Synthesis of the host-selective phytotoxin destruxin B. Avoiding diketopiperazine formation from an N-methyl amino acid dipeptide by use of the Boc-hydrazide derivative.Tetrahedron Letters, 38, 339-342.
Pedras, M. S. C.; Khan, A.Q.; Taylor, J.L. 1997. Phytoalexins from Brassicas: overcoming plants' defenses. In Phytochemicals for Pest Control; Hedin, P. A.; Hollingworth, R. M.; Masler, E. P.; Miyamoto, J.; Thompson, D. G. Eds.; ACS Symposium Series 658, 155-166 (REVIEW).
Pedras, M. S. C. 1996. Phytotoxins from phytopathogenic blackleg fungi. Revista Latinoamericana de Quimica, 24, 177-182 (REVIEW).
Ward, D. E.; Vazquez, A.; Pedras, M. S. C. 1996. Understanding host-selective phytotoxicity: synthesis and biological discrimination of phomalide and its (Z)-isomer. Journal of Organic Chemistry, 61, 8008-8009.
Pedras, M. S. C.; Khan, A. Q. 1996. Biotransformation of the Brassica Phytoalexin Brassicanal A by the Blackleg Fungus, Journal of Agricultural & Food Chemistry, 44, 3403-3407.
Pedras, M. S. C. 1996. The chemistry of cyclohexenediones produced by the blackleg fungus. Canadian Journal of Chemistry, 74, 1597-1601.
Pedras, M. S. C.; Taylor, J. L.; Morales, V. M. 1996. The blackleg fungus of rapeseed: how many species- Acta Horticulturae, 407, 441-446 (REVIEW).
Taylor, J. L.; Pedras, M. S. C.; Morales, V. M. 1995. Horizontal transfer in the phytopathogenic fungal genus Leptosphaeria and its correlation to host-range expansion. Trends in Microbiology, 3, 202-206.
Pedras, M. S. C.; Taylor, J.L.; Morales, V. M. 1995. Phomaligin A and other yellow pigments in Phoma lingam and P. wasabiae. Phytochemistry, 38, 1215-1222.
Pedras, M. S. C.; Morales, V. M.; Taylor, J. L. 1994. Phomapyrones: three metabolites from the "blackleg" fungus. Phytochemistry, , 36, 1315-1318.
Pedras, M. S. C.; McAfee, B. J.; Lapp, M. S. 1994. Biotransformation of 1-naphthaleneacetic acid by the ectomycorrhizal fungus Pisolithus arhizus.Phytochemistry, 36, 825-827.
Pedras, M. S. C.; Taylor, J. L.; Nakashima, T. T. 1993. A novel chemical signal from the blackleg fungus: beyond phytotoxins and phytoalexins. Journal of Organic Chemistry, 58, 4778-4780.
Pedras, M. S. C.; Morales, V. M.; Taylor, J. L. 1993. Phomaligols and phomaligadiones: new metabolites from the blackleg fungus. Tetrahedron, 37, 8317-8322.
Pedras, M. S. C.; Taylor, J. L. 1993, Metabolism of the phytoalexin brassinin by the 'blackleg fungus'. Journal of Natural Products, 56, 731-738.
Pedras, M. S. C.; Borgmann, I.; Taylor, J. L. 1992. Biotransformation of brassinin is a detoxification mechanism in the 'blackleg" fungus. Life Science Advances (Phytochemistry), 11, 1-7. (INVITED)
Pedras, M. S. C.; Seguin-Swartz, G. 1992. The "blackleg" fungus: phytotoxins and phytoalexins. Canadian Journal of Phytopathology, 14, 67-75. (REVIEW)
Pedras, M. S. C.; Taylor, J. L. 1991. Metabolic transformation of the phytoalexin brassinin by the 'blackleg fungus'. Journal of Organic Chemistry, 56, 2619-2621.
Kao, K. N.; Saleem, M.; Abrams, S.; Pedras, S.; Horn, D.; Mallard, C. 1991. Culture conditions for induction of green plants from barley microspores by anther culture methods. Plant Cell Reports, 9, 595-607.
Pedras, M. S. C. Seguin-Swartz 1990. Rapid high-performance liquid chromatographic analysis of phytotoxins from Phoma lingam. J. Chromatography, 519, 383-386.
Pedras, M. S. C.; Seguin-Swartz, G.; Abrams, S. R. 1990. Minor phytotoxins from the blackleg fungus Phoma lingam. Phytochemistry, 29, 777-782.
1989 - 1986
Pedras, M. S. C.; Abrams, S.R.; Seguin-Swartz, G.; Quail, J.W.; Jia, Z. 1989. Phomalirazine, a novel toxin from the phytopathogenic fungus Phoma lingam.Journal of the American Chemistry Society, 111, 1904-1905.
Pedras, M. S. C.; Abrams, S.R.; Seguin-Swartz, G. 1988. Isolation of the first naturally occurring epimonothiodioxopiperazine, a fungal toxin produced byPhoma lingam. Tetrahedron Letters, 29, 3471-3474.
Ayer, W. A.; Pedras, M. S. C.; Ward, D. E. 1987. Metabolites produced by the scleroderris canker fungus Gremmeniella abietina. Part 4. Biosynthetic studies. Canadian Journal of Chemistry, 65, 760-764. (PhD. project)
Ayer, W. A.; Pedras, M. S. C. 1987. Metabolites produced by the scleroderris canker fungus Gremmeniella abietina. Part 3. Some further metabolites.Canadian Journal of Chemistry, 65, 754-759. (PhD. project)
Ayer, W. A.; Hoyano, Y.; Pedras, M. S. C.; Clardy, J.; Arnold, E. 1987. Metabolites produced by the scleroderris Canker Fungus Gremmeniella abietina. Part 2. The structure of scleroderolide. Canadian Journal of Chemistry, 65, 748-753. (PhD. project)
Ayer, W. A.; Hoyano, Y.; Pedras, M. S. C.; van Altena, I. 1986. Metabolites produced by the scleroderris canker fungus Gremmeniella abietina. Part 1.Canadian Journal of Chemistry, 64, 1585-1589. (Ph.D. project)