Articles published or accepted

Trainees of Dr. Price are highlighted in bold, corresponding authors are indicated by *

2023:

  • Salih, A. K.; Garcia, M.D.; Raheem, S. J.; Ahiahonu, W. K.; Price, E. W.* DFO-Km: A Modular Chelator as a New Chemical Tool for the Construction of Zirconium-89-Based Radiopharmaceuticals. Inorg. Chem. 2023. DOI: 10.1021/acs.inorgchem.3c02714.
  • Raheem, S. J.; Salih, A. K.; Garcia, M. D.; Sharpe, J. C.; Toosi, B. M.; Price, E. W.* A Systematic Investigation into the Influence of Net Charge on the Biological Distribution of Radiometalated Peptides Using [68Ga]Ga-DOTA-TATE Derivatives. Bioconjugate Chemistry 2023. DOI: 10.1021/acs.bioconjchem.3c00007.
  • Khozeimeh Sarbisheh, E.; Summers, K. L.; Salih, A. K.; Cotelesage, J. J. H.; Zimmerling, A.; Pickering, I. J.; George, G. N.*; Price, E. W.* Radiochemical, Computational, and Spectroscopic Evaluation of High-Denticity Desferrioxamine Derivatives DFO2 and DFO2p toward an Ideal Zirconium-89 Chelate Platform. Inorg. Chem. 2023. DOI: 10.1021/acs.inorgchem.2c03573.
  • Aigbogun, O. P.; Phenix, C. P.; Krol, E. S.; Price, E. W.* The Chemistry of Creating Chemically Programmed Antibodies (cPAbs): Site-Specific Bioconjugation of Small Molecules. Mol. Pharm. 2023. DOI: 10.1021/acs.molpharmaceut.2c00821.
  • Carrasco, R. A.; Salih, A. K.; Garcia, M. D.; Khozeimeh Sarbisheh, E.; Adams, G. P.; Phenix, C. P.*; Price, E. W.* Development and Biodistribution of a Nerve Growth Factor Radioactive Conjugate for PET Imaging. Mol. Imaging Biol. 2023. DOI: 10.1007/s11307-023-01805-w.

2022:

  • Salih, A. K.; Raheem, S. J.; Garcia, M. D.; Ahiahonu, W. K.; Price, E. W.* Design, Synthesis, and Evaluation of DFO-Em: A Modular Chelator with Octadentate Chelation for Optimal Zirconium-89 Radiochemistry. Inorg. Chem. 2022, 61 (51), 20964-20976. DOI: 10.1021/acs.inorgchem.2c03442.

2021:

  • Bhanumathy, Kalpana K.; Abuhussein, Omar; Vizeacoumar, Frederick S.; Freywald, Andrew; Vizeacoumar, Franco J.; Phenix, Christopher P.; Price, Eric W.; Cao, Ran. Chapter 18 in the “Methods in Molecular Biology” series “Computational Prediction of Chemical Tools for Identification and Validation of Synthetic Lethal Interaction Networks” in the book “Mapping Getting Interactions”, edited by Vizeacoumar, Franco J.; Freywald, Andrew. Nature Springer, 2021, 333-358 DOI:10.1007/978-1-0716-1740-3_18.
  • Sharma, S. K.; Glaser, J. M.; Edwards, K. J.; Khozeimeh Sarbisheh, E.; Salih, A. K.; Lewis, J. S.*; Price, E. W.* A Systematic Evaluation of Antibody Modification and 89Zr-Radiolabeling for Optimized Immuno-PET. Bioconjugate Chem. 2021, 32 (7), 1177-1191. https://doi.org/10.1021/acs.bioconjchem.0c00087. This article is part of the State-of-the-Art of Radiometal-based Bioconjugates for Molecular Imaging and Radiotherapy special issue.
  • Raheem, S. J.; Schmidt, B. W.; Solomon, V. R.; Salih, A. K.; Price, E. W.*, Ultrasonic-Assisted Solid-Phase Peptide Synthesis of DOTA-TATE and DOTA-linker-TATE Derivatives as a Simple and Low-Cost Method for the Facile Synthesis of Chelator–Peptide Conjugates. Bioconjugate Chem. 2021, 32 (7), 1204-1213. https://doi.org/10.1021/acs.bioconjchem.0c00325. This article is part of the State-of-the-Art of Radiometal-based Bioconjugates for Molecular Imaging and Radiotherapy special issue.

2020:

  • Khozeimeh Sarbisheh, Elaheh; Dewaele-Le Roi, Guillaume; Shannon, Whitney E.; Tan, Sally; Xu, Yujia; Zeglis, Brian M*.; Price, Eric W*. DiPODS: A Reagent for Site-Specific Bioconjugation via the Irreversible Re-bridging of Disulfide Linkages. Bioconjugate Chemistry, 2020. https://doi.org/10.1021/acs.bioconjchem.0c00590.
  • Summers, Kelly L.; Khozeimeh Sarbisheh, Elaheh; Zimmerling, Amanda; Cotelesage, Julien J. H.; Pickering, Ingrid J.*; George, Graham N.*; Price, Eric W*. Structural characterization of the solution chemistry of zirconium(IV) desferrioxamine: A coordination sphere completed by hydroxides. Inorganic Chemistry, 2020. https://doi.org/10.1021/acs.inorgchem.0c02725.
  • Khozeimeh, E. S.; Salih, A. K.; Raheem, S. J.; Lewis, J. S.; Price, E. W.*, A High-Denticity Chelator Based on Desferrioxamine for Enhanced Coordination of Zirconium-89. Inorg Chem. 2020. https://doi.org/10.1021/acs.inorgchem.0c01629.
  • Fung, K.; Vivier, D.; Keinanen, O.; Khozeimeh, E. S.; Price, E. W.; Zeglis, B. M.* 89Zr-Labeled AR20.5: A MUC1-Targeting ImmunoPET Probe. Molecules, 2020, 25(10), 2315, https://doi.org/10.3390/molecules25102315.

2019:

  • Khozeimeh Sarbisheh, Elaheh; Price, Eric. W.*, The Radiopharmaceutical Chemistry of the Radioisotopes of Lutetium and Yttrium, in “Radiopharmaceutical Chemistry”, edited by Jason S. Lewis, Brian M. Zeglis, Albert D. Windhorst, Springer, https://doi.org/10.1007/978-3-319-98947-1, online ISBN 978-3-319-98947-1, 359-370, 2019. 
  • Andronowski, Janna M.*; Mundorff, Amy Z.; Davis, Reed A.; Price, Eric W.*, Application of X-ray Photoelectron Spectroscopy to Examine Surface Chemistry of Cancellous Bone and Medullary Contents to Refine Bone Sample Selection for Nuclear DNA Analysis. Anal. At. Spectrom. 2019, 34, 2074-2082.

2018:

  • Escorcia, Freddy E., Steckler, Jeffery M., Abdel-Atti, Dahlia, Price, Eric W., Carlin, Sean D., Scholz, Wolfgang W., et al. Tumor-Specific Zr-89 Immuno-PET Imaging in a Human Bladder Cancer Model. Mol Imaging Biol. 2018, 1-8. https://doi.org/10.1007/s11307-018-1177-z

2017:

  • Rempel, Brian P.; Price, Eric W.; Phenix, Christopher P. Molecular Imaging of Hydrolytic Enzymes Using PET and SPECT. Mol. Imaging.2017, 16, 1536012117717852.
  • Price, Eric W., Carnazza, Kathryn E., Carlin, Sean D., Cho, Andrew, Edwards, Kimberly J., Sevak, Kuntal K., Glaser, Jonathan M., de Stanchina, Elisa,  Janjigian, Yelena Y.,  Lewis, Jason S.
    89Zr-DFO-AMG102 Immuno-PET to Determine Local HGF Protein Levels in Tumors for Enhanced Patient Selection. J. Nucl. Med., 2017. DOI: 10.2967/jnumed.116.187310.

2016:

  • Price, Eric W., Edwards, Kimberly J., Carnazza, Kathryn E., Carlin, Sean D., Zeglis, B. M., Adam, M. Orvig, C. Lewis, J. S. A Comparative Evaluation of the Chelators H4octapa and CHX-A˝-DTPA with the Therapeutic Radiometal 90Y. Nuc. Med. Bio. 2016, 43 (9), 566-576.

2014:

  • Price, Eric W., Orvig, C.  The Chemistry of Inorganic Nuclides (86Y, 68Ga, 64Cu, 89Zr, 124I).  In The Chemistry of Molecular Imaging.  N. J. Long, W.-T. Wong, Eds. Wiley, 2014, 105-135.
  • Price, Eric W., Zeglis, B. M., Cawthray, J. F., Lewis, J. S., Adam, M. J., Orvig, C. What a Difference a Carbon Makes: H4octapa vs. H4C3octapa, Ligands for In-111 and Lu-177 Radiochemistry. Inorg. Chem. 2014, 53 (19), 10412-10431.
  • Price, Eric W., Cawthray, J. F, Adam, M. J., Orvig, C. Modular Syntheses of H4octapa and H2dedpa, and Yttrium Coordination Chemistry Relevant to 86/90Y Radiopharmaceuticals. Dalton Trans. 2014, 43 (19), 7176-7190.
  • Price, Eric W., Ferreira, C. L., Adam, M. J., Orvig, C. High Denticity Ligands Based on Picolinic Acid for In-111 Radiochemistry. Can. J. Chem. 2014, 92 (8), 695-705 (invited Barry Lever special issue). 
  • Price, Eric W., Zeglis, B. M., Lewis, J. S., Adam, M. Orvig, C. H6phospa-Trastuzumab: Bifunctional Methylenephosphonate-based Chelator with 89Zr, 111In and 177Lu. Dalton Trans. 2014, 43 (1), 119-131. 
  • Price, Eric W., Orvig, C. Matching Chelators to Radiometals for Radiopharmaceuticals. Chem. Soc. Rev. 2014, 42 (1), 260-290.

2013:

  • Price, Eric W.; Zeglis, B. M.; Cawthray, J. F.; Ramogida, C. F.; Ramos, N.; Lewis, J. S.; Adam, M. J.; Orvig, C., H4octapa-Trastuzumab: The Application of a Versatile Acyclic Chelate System for 111In and 177Lu Imaging and Therapy. J. Am. Chem. Soc. 2013,135 (34), 12707–12721.

2012:

  • Boros, E.; Ferreira, C. L.; Yapp, D. T. T.; Gill, R. K.; Price, Eric W.; Adam, M. J.; Orvig, C., RGD conjugates of the H2dedpa scaffold: synthesis, labeling and imaging with 68Ga. Nucl. Med. Biol. 2012, 39 (6), 785-794. 
  • Bailey, G. A.*; Price, Eric W.*; Zeglis, B. M.; Ferreira, C. L.; Boros, E.; Lacasse, M. J.; Patrick, B. O.; Lewis, J. S.; Adam, M. J.; Orvig, C., H2azapa: a Versatile Acyclic Multifunctional Chelator for 67Ga, 64Cu, 111In, and 177Lu. Inorg. Chem. 2012, 51 (22), 12575-12589. *These authors contributed equally to this work. 
  • Price, Eric W.; Cawthray, J. F.; Bailey, G. A.; Ferreira, C. L.; Boros, E.; Adam, M. J.; Orvig, C., H4octapa: An Acyclic Chelator for 111In Radiopharmaceuticals. J. Am. Chem. Soc. 2012, 134 (20), 8670-8683. 

2011:

  • Price, Eric W.; Harirchian-Saei, S.; Moffitt, M. G., Strands, Networks, and Continents from Polystyrene Dewetting at the Air-Water Interface: Implications for Amphiphilic Block Copolymer Self-Assembly. Langmuir 2011, 27 (4), 1364-1372. Invited manuscript for ACS Langmuir special issue: Supramolecular Chemistry at Interfaces. 

2010:

  • Boros, E.; Ferreira, C. L.; Cawthray, J. F.; Price, Eric W.; Patrick, B. O.; Wester, D. W.; Adam, M. J.; Orvig, C., Acyclic Chelate with Ideal Properties for 68Ga PET Imaging Agent Elaboration. J. Am. Chem. Soc. 2010, 132 (44), 15726-15733.

2009:

  • Price, Eric W.; Guo, Y.; Wang, C. W.; Moffitt, M. G., Block Copolymer Strands with Internal Microphase Separation Structure via Self-Assembly at the Air-Water Interface. Langmuir 2009, 25 (11), 6398-6406. (NSERC USRA funded undergraduate research term).

Patents

  • M. Adam; E. Boros; C. L. Ferreira. C. Orvig; E. W. Price.  Bifunctional Chelating Agents. EP Patent 2,536,691, USA #20110313130 A1, published December 22, 2011, International WO2011100829 A1, published August 25, 2011.
  • M. Adam, E. Boros, C. L. Ferreira, C. Orvig, E. W. Price.  Bifunctional Chelating Agents.  U.S. Patent 8,772,446 issued 2014/07/08.