Primary Investigator: Dr. Lissa Peeling
Intracerebral hemorrhage (ICH) is caused by the rupture of a blood vessel, resulting in bleeding into the brain. This type of stroke accounts for 12-15% of all strokes and is the most fatal type of stroke (40% mortality rate). ICH stroke presents a greater burden to survivors as 90% of ICH survivors have some degree of disability. Currently, there are no effective, proven treatments for these patients that provide good outcomes. Because of the poor patient outcomes, there is a clear need for identifying new treatments as well as establishing the efficacy of existing treatments - treatments such as "evacuation”, where the pooled blood is removed from the brain. Dr. Peeling’s research aims to establish a mouse model of ICH at the University of Saskatchewan, using collagenase injection.