Phenogenomic Imaging Centre of Saskatchewan (PICS) - Based at the University of Saskatchewan, our centre provides specialist support to help the Saskatchewan scientific community in carrying out high-throughput RNAi and CRISPR screens with human cells. We support both high-content microscopy as well as infrastructure needed to process these samples in a high-throughput fashion. This can either be used to identify genes involved in disease representing future drug targets, or to identify genes involved in biological processes.
We offer logistical, technical, and bioinformatic support in order to assist screeners in performing and interpreting their genome scale assays including...
- CRISPR-Cas9 gene editing technology
- Lentiviral-based gene knockdown assays
- Pooled shRNA microarray screenings
- High-Content Screening
Next-Generation Sequencing Facility (NGSF) - A high-throughput genomics facility located at the University of Saskatchewan. It is supported by the Saskatchewan Cancer Agency and University of Saskatchewan College of Medicine. The primary goal of the NGSF is to further basic and clinical research by providing access to high-throughput sequencing technologies and expertise.
In addition to library preparation and sequencing services, data analysis and bioinformatics services are also available, either together or each independently.