Wu lab - J Biol Chem paper
Helicases in R-loop Formation and Resolution
Recent news and publications from the Cancer Cluster
Helicases in R-loop Formation and Resolution
BRK confers tamoxifen-resistance in breast cancer via regulation of tyrosine phosphorylation of CDK1
Integration of cancer-related genetic landscape of Eph receptors and ephrins with proteomics identifies a crosstalk between EPHB6 and EGFR
A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy
Seeking a better understanding of the non-receptor tyrosine kinase, SRMS
A CRISPR Platform for Targeted In Vivo Screens
Synthetic lethal interactions of DEAD/H-box helicases as targets for cancer therapy
Homoharringtonine demonstrates a cytotoxic effect against triple-negative breast cancer cell lines and acts synergistically with paclitaxel
Development of 3D tissue engineered tumour microtissue models for precision medicine
The Critical Role of AMPKα1 in Regulating Autophagy and Mitochondrial Respiration in IL-15-Stimulated mTORC1Weak Signal-Induced T Cell Memory: An Interplay between Yin (AMPKα1) and Yang (mTORC1) Energy Sensors in T Cell Differentiation
Triple negative breast cancer: approved treatment options and their mechanisms of action
A Drug Repurposing Screen Identifies Fludarabine Phosphate as a Potential Therapeutic Agent for N-MYC Overexpressing Neuroendocrine Prostate Cancers