New Research Findings Published in Nature Communications!

Our latest research showing hnRNP A1 dysfunction alters RNA splicing and drives neurodegeneration in multiple sclerosis (MS) has just been published with Springer Nature in Nature Communications! In this article, advanced RNA sequencing and CLIPseq of MS brains and relevant models demonstrate that hnRNP A1 binding of target RNAs and RNA splicing were altered, precipitating neurodegeneration in MS. Read it here: https://rdcu.be/dvqwA

Dr. Cole Libner Wins Whitaker Award at CMSC

Congratulations to our summer medical student, Dr. Cole Libner, on winning the Whitaker Award at the Consortium of Multiple Sclerosis Centers (CMSC) Conference in Nashville, TN for Best Trainee Research Presentation!

Kaitland Fior Awarded NSERC USRA!

Congratulations to our honour's project student, Kaitland Fior, on winning an NSERC Undergraduate Student Research Award for her upcoming summer research project!

TEDx 2024

Congratulations to Dr. Levin for being selected to give a TEDx talk at USASK on January 21, 2024.

Miranda Messmer Awarded the Raifta Shwedyk Bursary Fund!

Congratulations to our graduate student, Miranda Messmer, on being awarded the Raifta Shwedyk Bursary Fund! This bursary makes a donation toward the endMS National Training Program to sponsor a student trainee attending the endMS Summer School from a university in Manitoba or Saskatchewan.

Dr. Hannah Salapa Wins 10X Genomics Single Cell Grant Competition!

Congratulations to our Professional Research Associate, Dr. Hannah Salapa, on winning the 10X Genomics Single Cell Grant competition! This grant is funded by 10X Genomics and the University of Saskatchewan Next-Generation Sequencing Facility to support creative and innovative single cell sequencing pilot projects.

Dr. Cole Libner Selected as FCMSC Research Scholar!

Congratulations to Dr. Cole Libner on being selected as a Foundation of the Consortium of Multiple Sclerosis Centers Research Scholar! Cole completed his PhD with us last year before starting medical school at the University of Saskatchewan. He has returned to the lab this summer to complete a research project titled, "Novel small molecule therapy to inhibit neurodegeneration in an in vivo model of multiple sclerosis."

Dr. Joseph P. Clarke's Latest Paper Accepted to Frontiers in Molecular Biosciences!

Congratulations to our post-doctoral fellow, Dr. Joseph P. Clarke, on the acceptance of his paper titled, "Sequence- and structure-specific RNA oligonucleotide binding attenuates heterogeneous nuclear ribonucleoprotein A1 dysfunction" to the journal Frontiers in Molecular Biosciences! In a cellular model that imitates aspects of MS, Dr. Clarke and colleagues demonstrated that RNA oligonucleotides attenuate heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) dysfunction and its detrimental downstream cellular effects. This is important because hnRNPA1 dysfunction has been shown to contribute to the pathogenesis of MS and using RNA oligonucleotides to disrupt hnRNPA1 dysfunction may be used as a treatment for MS.

Tackling Neurodegeneration in MS Through A1 Antibodies

Dr. Michael Levin, professor of neurology at the University of Saskatchewan, discussed his presentation at the 2022 CMSC Annual Meeting on using ribonucleoprotein A1 antibodies to drive neurodegeneration in multiple sclerosis.

Dr. Michael Levin on John Gormley Live!

The province of Saskatchewan has some of the highest rates of Multiple Sclerosis in Canada. A recent study that was published in the Journal of Science states that the Epstein-Barr virus (which causes mononucleosis) or mono, acts as an environmental trigger for Multiple Sclerosis. Dr. Michael Levin, the Saskatchewan MS Clinical Research Chair and professor at the University of Saskatchewan joins us live in Studio to answer all MS related questions.

Todd Stang Wins 3rd Place at SURE Symposium

Congratulations to our summer student, Todd Stang, on winning 3rd Place at the Student Undergraduate Research Experience Summer Symposium! Todd's project is titled, "Exploring the Role of Nucleocytoplasmic Transport Changes in Neuronal Cell Damage in Models of Nervous System Disease."

SK MS Office Team Member Among 2020-2021 endMS SPRINTers

Cole Libner, University of Saskatchewan student and team member in the Office of the Saskatchewan MS Clinical Research Chair, is among the successful applicants for the endMS Scholar Program for Researchers IN Training (SPRINT).

Researching MS treatments

Dr. Levin discusses MAD4MS Comedy Night Fundraiser, and his teams latest work and discoveries in MS Research

MS and a Money-Raising Heifer

The University of Saskatchewan multiple sclerosis research team was the recipient of a unique fundraising event earlier this year

Media Release from the U of S

On September 12, the University of Saskatchewan put out a media release announcing Dr. Levin's most recent discovery.